A group of researchers led by Frank and Zoe have achieved the unimaginable- bringing the dead back to life. After a successful, yet unsanctioned, trial on a deceased animal, the team is ready to unveil their breakthrough. When the dean of their university learns of their experiments, their project is shut down. The team recreates the experiment, but things go wrong and Zoe is horrifically killed. Fueled by terror and grief, Frank attempts to resurrect their first human subject. The procedure appears a success, but the team soon realizes something is wrong with Zoe. As her strange new persona reveals itself, the team is no longer faced with the question of whether they can bring someone back to life- but rather, the wrath of her return.